Structural Insights into a Unique Dimeric DEAD-Box Helicase CshA that Promotes RNA Decay |
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Authors: Jennifer Huen, Chia-Liang Lin,Bagher Golzarroshan, Wan-Li Yi,Wei-Zen Yang, Hanna S. Yuan |
In
Brief: Huen et al. report the crystal structure of CshA, a unique dimeric DEAD-box helicase. CshA binds RNA with or without ATP/ADP, as RNA remain bound with CshA during ATP hydrolysis cycles. RNA is thus degraded processively through cooperation between exoribonucleases and CshA in the RNA-degrading machinery. |
Highlights
Accession Numbers 5IVL Huen et al., 2017, Structure 25, 1–13 March 7, 2017 ª 2017 Elsevier Ltd. http://dx.doi.org/10.1016/j.str.2017.01.012 |