Publications (2002-1991)

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Structural studies of the pigeon cytosolic NADP(+)-dependent malic enzyme.

Yang Z., Zhang H., Hung H. C., Kuo, C. C., Tsai, L. C., Yuan, H. S, Chou, W. Y., Chang, G. G., Tong, L.

Protein Sci., 11:332-41 (2002)

Directed mutagenesis of specific active site residues on Fibrobacter succinogenes 1,3-1,4-beta-D-glucanase significantly affects catalysis and enzyme structural stability.

Chen, J. L., Tsai, L. C., Wen, T. N., Tang, J. B., Yuan, H. S. and Shyur, L. F.

J. Biol. Chem., 276 , 17895-17901 (2001)

Crystallization and preliminary X-ray diffraction analysis of the 1,3-1,4-beta-D-glucanase from Fibrobacter succinogenes.

Tsai, L. C., Shyur, L. F., Lin, S. S., Yuan, H. S.

Acta Cryst. D57: 1303-1306 (2001)

Structure analysis of the transcriptional activation region on Fis: Crystal structures of Six Fis Mutants with Different activation properties.
Cheng, Y.-S., Yang, W.-Z., Johnson, R. C. and Yuan, H. S.
J. Mol. Biol., 302, 1139-1151 (2000).

The crystal structure of the DNase domain of colicin E7 in complex with its inhibitor Im7 protein.
Ko, T.-P., Liao, C.-C., Ku, W.-Y., Chak, K.-F. and Yuan, H. S.
Structure, 7, 91-102 (1999).

Crystallization and preliminary x-ray diffraction analysis of malic enzyme from pigeon liver.
Tsai, L.-C, Kuo, C.-C., Chou, W.-Y., Chang, G.-G. and Yuan, H. S.
Acta Cryst. D55, 1930-1932 (1999).

The preliminary crystallographic analysis of the open-form E. coli tyrosine aminotransfer ase bound with a cofactor pyridoxal 5'-phosphate.
Ko, T. P., Yang, W.-Z, Wu, S.-P., Hsin, T., and Yuan, H. S.
Acta Cryst. D55, 1474-1477(1999).

Hierarchical order of critical residues on the immunity-determining region of the Im7 protein which confer specific immunity to its cognate colicin.
Lu, F.-M., Yuan, H. S., Hsu, Y.-C., Chang, S.-J., Chak, K.-F.
Biochem-Biophys-Res-Commun., 264, 69-75 (1999).

Inolving the x-ray phase problem of macromolecular crystals by stereoscopic multi-beam imaging.
Chang, S.-L., Chao, C.-H., Huang, Y.-S., Jean, Y.-C., Sheu, H.-S., Liang, F.-J., Chen, C.-K., Yuan, H. S.
Acta. Cryst. A55, 933-938 (1999).

Expression, crystallization and preliminary x-ray diffraction studies of N- carbamyl-D-amino-acid amidohydrolase from Agrobacterium radiobacter.
Hsu, W.-H., Chien, F.-T., Hsu, C.-L., Wang, T.-C., Yuan, H. S., and Wang, W.-C.
Acta. Cryst. D55, 694-695 (1999).

The conversion from a beta-strand to an alph-helix induced by a single-site mutation identified in the crystal structures of Fis mutant Pro26Ala.
Yang, W.-Z, Ko, T. P., Corselli, L., Johnson, R. C. and Yuan, H. S. 
Protein Science 7, 1875-1883 (1998).

The transactivation region of the Fis protein that controls site-specific DNA inversion contains extended mobile beta-hairpin arms.
Safo, M. K., Yang, W.-Z., Corselli, L., Crampton, S., Yuan, H. S., and Johnson, R. C.
EMBO J. 16, 22, 6860-6873 (1997).

A novel role of ImmE7 in the autoregulatory expression of ColE7 operon and identification of possible ribonuclease active sites in the crystal structure of dimeric ImmE7.
Hsieh, S.-H., Ko, T.-P., Tseng, M.-Y., Ku, W.-Y., Chak, K.-F, and Yuan, H. S.
EMBO J. 16, 1444-1454 (1997).

A brief introduction to protein crystallography using ImmE7 as an example.
Ko, T.-P. and Yuan, H. S.
Chemistry, 55, 1-8 (1997).

The crystal structure of the ImmE7 protein suggests a possible colicin-interacting surface.
Chak, K.-F., Safo, M. K., Ku, W.-Y., Hsieh, S.-Y., and Yuan, H. S.
Proc. Natl. Acad. Sci. USA, 93, 6437-6442 (1996).

The crystal structure of dimeric ImmE7 presents possible ribonuclease active sites.
Ko, T.-P., Ku, W.-Y., and Yuan, H. S.
Proceedings of the fourth R.O.C.-Japan Joint Seminar on crystallography ,43-54 (1996).

Crystallization and preliminary crystallographic analysis of ImmE7 protein of Colicin E7.
Ku, W. Y., Wang, C. S., Chen, J. Y., Chia, K. F., Safo, M. K., and Yuan, H. S.
Proteins, Struc. Func. & Genet. 23, 588-590 (1995).

The structure of Fis mutant Pro61-Ala illustrates that the kink within the long a-helix is not due to the presence of the proline residue.
Yuan, H. S., Yang, W.-Z., Wang, S. S., Finkel, S. E. and Johnson, R. C.
J. Biol. Chem. 269, 46, 28947-28954, (1994).

Determination of the absolute configuration of (S)-(+)-neopentyl-1-d alcohol by neutron diffraction study of strychnium neopentylphthalate.
Yuan, H. S., Stevens, R. C., Kotzle, T. F. and Bau, R.
Proc. Natl. Acad. Sci. USA , 91, 12872-12876, (1994).

The structure of a decamer with an alternating AT sequence : C-G-A-T-A-T-A-T-C-G.
Yuan, H. S., Quintana, J. and Dickerson, R. E.
Biochemistry, 31,34, 8009-8021, (1992).

The molecular structure of wild-type and a mutant Fis ; Relationship between mutational changes and recombinational enhancer function or DNA binding.
Yuan, H. S., Finkel, S. E., Feng, J.-A., Kaczor-Grzeskowiak, M., Johnson, R. C. and Dickerson, R. E.
Proc. Natl. Acad. Sci. USA, 88, 9558, (1991).